DHT - cause hair loss but not only. What else you need to know ?

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Understanding DHT: The Hormone Behind Hair Loss, Prostate Issues, and Hormonal Imbalance
If you're experiencing hair loss, especially male pattern baldness or female hair thinning, you've probably heard of DHT. This powerful hormone is at the center of many hair loss cases, as well as prostate enlargement and conditions like PCOS. But what exactly is DHT, and how does it affect your body — and your scalp?
Whether you’re considering hair transplant surgery, looking into DHT blocker treatments, or simply trying to understand why your hair is thinning, this guide will help clarify the role of DHT and how to manage its effects.
What is DHT and Why is it Important?
Dihydrotestosterone (DHT) is a hormone made from testosterone by an enzyme called 5-alpha-reductase. It’s much stronger than testosterone and is responsible for developing male characteristics, like facial hair, a deep voice, and increased muscle mass during puberty.
DHT is crucial for:
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Male genital development in the womb
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Puberty-related changes such as facial/body hair growth
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Normal prostate function
While DHT plays a helpful role early in life, too much of it — or increased sensitivity to it — can lead to issues like hair loss and prostate problems, especially as you age.
How Does DHT Cause Hair Loss?
DHT is the leading cause of androgenetic alopecia, also known as male pattern baldness and female pattern hair loss.
Here's how it works:
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DHT binds to receptors in your hair follicles, especially in the scalp's crown and hairline areas.
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In people with genetic sensitivity, DHT causes follicles to shrink — a process called miniaturization.
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Over time, hair becomes thinner, shorter, and eventually stops growing.
Important note: Hair loss doesn’t always mean high DHT levels in the blood. Some people have normal hormone levels but hypersensitive DHT receptors, which is why hair loss patterns vary from person to person.
DHT and Hair Transplants: Why You Still Need DHT Control
Even after a hair transplant, managing DHT is critical. If DHT is still active in the scalp, it can continue to shrink surrounding hair follicles, eventually affecting not transplanted hairs if not managed properly.
That’s why many hair restoration clinics recommend ongoing treatment with DHT blockers after a transplant to preserve long-term results.
DHT and the Prostate
DHT doesn't just affect the scalp. It's also responsible for the growth of the prostate gland. As men age, high DHT activity in the prostate can lead to:
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Benign prostatic hyperplasia (BPH) — an enlarged prostate
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Urinary symptoms and sexual dysfunction
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Increased risk of prostate cancer in some individuals
DHT and PCOS in Women
Although DHT has limited roles in female physiology, it can become problematic in conditions like Polycystic Ovary Syndrome (PCOS).
In women with PCOS, DHT may:
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Cause excess facial and body hair (hirsutism)
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Lead to acne, irregular periods, and hair thinning
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Worsen insulin resistance and contribute to weight gain
These hormonal imbalances can be subtle but significantly impact health and appearance.
Treatment Options: How to Block DHT
1. Prescription Medications (DHT Blockers)
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prescribed medications (Finaster..) Inhibits 5-alpha-reductase type 2. Effective in treating hair loss and prostate issues.
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prescribed medication (Dutaster...): Blocks both type 1 and type 2 enzymes. Often used in more advanced hair loss or BPH.
* I am noticing full names of medications because promoting medications is forbidden.
These medications are commonly used in hair loss clinics and trichology practices and are often prescribed alongside hair transplant procedures.
However, they may cause side effects in some people, including:
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Reduced libido
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Erectile dysfunction
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Mood changes
2. Topical DHT Blockers
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Shampoos and serums containing saw palmetto, caffeine, pumpkin seed oil, or green tea extract may reduce DHT activity on the scalp.
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These are often used as home care support in early-stage hair thinning or alongside professional treatments.
3. Natural Supplements for Hair Loss
Many clients prefer non-pharmaceutical options due to concerns about side effects. Popular natural DHT blockers include:
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Zinc
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Reishi mushroom
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Pygeum
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Stinging nettle root
These supplements are commonly found in hair growth support programs and may help balance hormone activity naturally.
Final Thoughts: DHT Is Powerful — But Manageable
DHT is a vital hormone, but in excess or when your body is overly sensitive to it, it can cause:
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Hair thinning or balding
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Prostate enlargement
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Hormonal imbalance in women (PCOS)
Not every client responds the same way to medication. Some may experience side effects, and in others, prescription DHT blockers may not work at all. That’s why it’s important to approach treatment holistically — combining medical options, targeted supplementation, and DHT-blocking hair care products tailored to your needs.
Whether you're dealing with early hair loss, considering a hair transplant, or managing PCOS symptoms, working with a qualified trichologist or specialist can help you choose the right strategy — with your individual hormone profile in mind.
Source : https://www.ncbi.nlm.nih.gov/books/NBK557634/
Please note: The information provided here is for informational purposes only and does not constitute medical advice. If you have any serious health issues, are taking medications, or have concerns about your health, please consult your GP or a medical advisor.