Treatments for Hair loss and androgenetic alopecia

Treatments for Hair loss and androgenetic alopecia
Androgenetic Alopecia (AGA), commonly known as male pattern baldness, extends beyond just aesthetic concerns. It reveals potential markers and associations with various health conditions, necessitating a comprehensive approach to its management.

Risk Factors and Associations:

Early-onset vertex balding may serve as an indicator for early-onset coronary heart disease, especially in young men with hypertension or dyslipidemia. Additionally, men with early AGA (before 35 years) face an increased risk of hyperinsulinemia and disorders linked to insulin resistance, such as obesity, hypertension, and dyslipidemia. The connection between AGA, prostate cancer, coronary heart disease, and insulin resistance underscores the need for further exploration into shared androgen pathways.

Understanding AGA Treatment:

AGA is a progressive condition, with an approximate 6% decrease in hair density per year. However, there are approved pharmaceutical treatments that can help manage AGA effectively.

1. "Fina....."  C23H36N2O2 a medication for hypertension, was serendipitous pharmaceutical discovery for hair loss.

  • Overview: A synthetic azo-steroid used since 1997, finasteride is a potent 5a-reductase type-2 inhibitor, reducing DHT concentration in the scalp and serum by over 60%.
  • Effectiveness: Studies show that  "F" can stabilize hair loss in 80% of patients with vertex hair loss and 70% with frontal hair loss, with a chance of mild to moderate regrowth.
  • Usage: Daily use is recommended for optimal results.
  • Side Effects and Risks:
    • Rare side effects include decreased libido and erectile dysfunction in a small percentage of users.
    • Some users may experience decreased ejaculate volume.
    • "F" does not significantly impact spermatogenesis or semen production.
    • Long-term side effects are not well-documented; however, a 7-year study with 5 mg of finasteride suggested a potential preventive effect on prostate cancer but a slight increase in high-risk cases.

2. "Min.... " mysterious ingredient hidden under the name 2,4-Diamino-6-piperidinopyrimidine 3-oxide

  • Overview: A biologic response modifier, minoxidil halts AGA progression and promotes hair regrowth. Available in 2% and 5% topical treatments, it is applied directly to the scalp.
  • Effectiveness: Clinical studies demonstrate moderate to dense regrowth in 30% to 35% of patients using the 2% solution.
  • Usage: Applied twice daily, "M" requires consistent, lifelong use.
  • Side Effects and Risks:
    • Side effects are minimal, with contact dermatitis reported in some cases.
    • Less than 1 in 1000 patients may experience tachycardia and decreased blood pressure.
    • Patients with hypotension or heart problems should use the medication cautiously.
    • Increased shedding may occur in the initial months of treatment, indicating anagen induction.

Hair Restoration Surgery:

For those seeking a permanent solution, hair restoration surgery, including hair transplantation, emerges as a successful option for suitable candidates. Techniques like strip harvesting and follicular unit extraction offer viable choices, and combining surgery with medical treatment yields optimal results.

Tailored Home Care and Trichological Treatments:

Understanding the complexity of your scalp is the first step. Tailored home care, such as double cleansing with professional trichological products, scalp peels, and specific shampoos, provides a proactive approach. Weekly or bi-weekly application of scalp masque peels, followed by conditioner and lotion, enhances the overall health of your scalp.

Elevating Scalp Health: Tailored Home Care and Trichological Treatments

In our pursuit of radiant skin, we've become adept at double cleansing our faces, investing in premium skincare. Yet, do we extend the same care to the often-neglected skin on our scalp? Let's unravel the intricacies: each hair, a single follicle, housing its intricate system of blood vessels, arrector pili muscles, stem cells, and sebaceous glands—a bustling factory beneath the surface.

Understanding the Complexity: The scalp, akin to facial skin, is endowed with sweat glands, dead epidermal cells, and more. It begs the question: Do you truly comprehend the complexity of your scalp? Can you identify your scalp type and provide it with the tailored care it deserves? And for those grappling with Androgenetic Alopecia (AGA), are you equipped to manage it effectively?

The First Step—Double Wash: For those battling AGA, a fundamental step is the double wash. The initial wash serves as a preparatory phase, eliminating oil and dirt, laying the groundwork for the crucial second wash. The second wash, often underestimated, produces a richer foam, a key factor in achieving a clean scalp.

Choosing Professional Trichological Products: Crucial to this process is the choice of products. I advocate for the use of professional trichological products, specially formulated to address scalp needs. Here, it's essential to recognize that shampoo is for the scalp, not just the hair; cleanliness is achieved during the journey.

Embracing the Essentials—Sebum Regulating Shampoo: In AGA cases, where an oily scalp is a frequent companion, the second wash is complemented by ATP Oxygen Equilibrium shampoo, designed to regulate sebum. This dynamic duo ensures a thorough cleanse.

Unveiling the Power of Scalp Peel Dermo Capillary Masque: To enhance the cleansing ritual, integrate the scalp peel dermo capillary masque. Laden with antibacterial and antifungal properties, this masque eliminates dead cells, unclogs blocked follicles, paving the way for active ingredients like lotions to perform their magic.

Customizing Care—Frequency Matters: The frequency of scalp masque peels hinges on individual needs. Are you a weekly warrior, akin to your face peel routine? Perhaps bi-weekly or monthly suits you better. Align your scalp care with your facial routine for optimal results.

The Ritual—From Peel to Lotion: Imagine a soothing 20-minute sanctuary under plastic foil post-peel. Rinse, double wash, and on the damp yet delicately dried hair, grace it with conditioner. After another 20 minutes, rinse again. But the crowning glory lies in applying lotion to the still-wet scalp—a bespoke elixir for revitalization.

Considerations—Contraindications and Risks: As with any beauty regimen, certain contraindications exist. Pregnancy, sensitivity to active ingredients, and active scalp diseases warrant caution. The risk? A bounty of strong, stimulated hair follicles.

AGA demands a multifaceted approach, combining medical treatments, surgical options, and personalized home care. By delving into the intricacies of these treatments, individuals can navigate AGA with informed choices, promoting not only aesthetic well-being but potentially impacting broader health aspects. Embrace the journey to healthier hair and scalp, recognizing the power of tailored care and the diverse solutions available. Always consult with healthcare professionals to assess individual risks and benefits. In unveiling this holistic approach to scalp care, we beckon you to a journey of not just arresting hair loss but embracing a crown of vitality. For each strand narrates a story, and through personalized care, we script a tale of resilience, strength, and enduring beauty.

Please note: The information provided here is for informational purposes only and does not constitute medical advice. If you have any serious health issues, are taking medications, or have concerns about your health, please consult your GP or a medical advisor.

 

 Source:
Buhl AE, Waldon DJ, Baker CA, et al. Minoxidil sulfate is the active metabolite that stimulates hair follicles. J Invest Dermatol.
Wester RC, Maibach HI, Guy RH, et al. Minoxidil stimulates cutaneous blood flow in human balding scalps: pharmacodynamics measured by laser doppler velocimetry and photopulse plethysmography. J Invest Dermatol.
Alert F. An open, randomized, comparative study of oral finasteride and 5% topical minoxidil in male androgenetic alopecia. Dermatology.
Bouhanna P. Topical minoxidil used before and after hair transplantation. J Dermatol Surg Oncol.
Martinick JH. The latest developments in surgical hair restoration. Facial Plast Surg Clin North Am 2004.
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1 comment

This website and the blog is my absolute guru when it comes to tacking my hair loss problems ! Finally someone cared and ‘designed ‘ my daily regimen and hair plan ! Thabk you !

Sylvia Ziaja

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